Fig. 6
From: IGF1 gene is epigenetically activated in preterm infants with intrauterine growth restriction
Haplotype methylation analysis of individuals. C represents a methylated CpG site, and T represents an unmethylated CpG site. CCCCCC means CG107, CG137, CG207, CG218, CG224, and CG232 were methylated, respectively. The frequency of each haplotype was shown as a heatmap. Hierarchical cluster analysis revealed a cluster surrounded by green where IUGR infants were dominant and relatively high TTTTTT and low CCCCCC were seen. There were two clusters surrounded by blue where non-IUGR infants were dominant and relatively high CCCCCC and low TTTTTT were seen