Fig. 5
From: IGF1 gene is epigenetically activated in preterm infants with intrauterine growth restriction
Methylation of six CpG sites of infants in the IUGR and non-IUGR groups. Methylation was significantly lower in the IUGR group than in the non-IUGR group in all six CG sites (CG108, 0.63 [0.54, 0.69] vs 0.71 [0.65, 0.75], p < 0∙001; CG137, 0.67 [0.58, 0.73] vs 0.77 [0.70, 0.80], p < 0.001; CG207, 0.45 [0.39, 0.51] vs 0.52 [0.46, 0.55], p = 0.012; CG218, 0.65 [0.60, 0.72] vs 0.73 [0.65, 0.76], p = 0.028; CG224, 0.64 [0.56, 0.69] vs 0.70 [0.64, 0.76], p = 0.010; CG232, 0.69 [0.60, 0.74] vs 0.75 [0.67, 0.79], p = 0.028, median [25%, 75%], IUGR group vs non-IUGR group, respectively)