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Fig. 4 | Clinical Epigenetics

Fig. 4

From: H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts

Fig. 4

Functional analysis based on genes identified from DARs. a Top enriched Pathways and GO Biological Process based on 1924 annotated genes in the vicinity of hyperacetylated regions that locate within a ± 5 kb range from the transcription start site. b Top enriched Pathways and GO Biological Process based on 5885 annotated genes in the vicinity of hypoacetylated regions that locate within a ± 5 kb range from the TSS. c Interaction of extracellular matrix-related genes, including TGFβ pathway associated genes and a cluster of collagen encoding genes detected (STRING). d Interaction of genes that are involved in the wound healing process, gene-encoded proteins in platelet activation are indicated in red nodes (STRING)

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Clinical Epigenetics

ISSN: 1868-7083

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