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Table 1 Characteristics of the study sample from the NICHD fetal Growth Studies–Singletons (n = 260)

From: Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation

 

Mean ± SD or N (%) or Median [p25-p75]

Maternal age, years

27.6 ± 5.2

Gestational age at enrollment, weeks

12.7 ± 0.9

Maternal pre-pregnancy BMI, kg/m2

23.3 ± 2.9

Maternal race/ethnicity

 Non-Hispanic White

67 (25.8)

 Non-Hispanic Black

59 (22.7)

 Hispanic

86 (33.1)

 Asians

48 (18.5)

Parity

 Nulliparous

126 (48.5)

 Parous

134 (51.5)

Infant sex

 Male

130 (50.0)

 Female

130 (50.0)

Maternal POP plasma concentration

Chemical class

Chemicals

 

  OCPs (ng/g)

  HCB

6.28 [3.50, 10.10]

 

  Trans-nonachlor

4.25 [2.48, 7.35]

 

p,p′-DDE

85.26 [54.09, 218.81]

 

  Σ OCPs

98.83 [65.70, 228.20]

  PBDEs (ng/g)

  PBDE 47

8.64 [3.60, 16.67]

  PCBs (ng/g)

  PCB 138/158

5.03 [2.78, 8.17]

 

  PCB 153

5.74 [3.18, 10.09]

 

  PCB 180

3.30 [1.90, 5.25]

 

  Σ PCBs

14.13 [8.06, 23.24]

  PFASs (ng/mL)

  PFDA

0.24 [0.16, 0.42]

 

  PFHxS

0.70 [0.43, 1.27]

 

  PFNA

0.75 [0.54, 1.22]

 

  PFOA

2.20 [1.30, 3.07]

 

  PFOS

4.74 [3.20, 7.65]

 

  PFUnDA

0.16 [0.09, 0.32]

 

  Σ PFASs

9.33 [6.39, 14.09]

  1. All POP concentrations were based upon machine-measured concentrations without substitution of concentrations < LOQ. OCPs, PCBs, and PBDEs concentrations are adjusted for total plasma lipids. Missing data have been imputed
  2. POP persistent organic pollutant