Fig. 5

G ×Me effect between rs3758249 in FOXE1 and the methylation level at the CpGs from the gene region. The x-axis groups the results into the unstratified dataset “all” and the results for each stratum: “1” denoting low methylation level, “2” — medium, and “3” — high methylation level. The minor and reference alleles are given for each group, along with their frequencies. The y-axis shows the relative risk on a log scale, with “c” denoting the child effect when only one minor allele is inherited (single dose) and “cdd” denoting the child effect when two such alleles are inherited (double dose)