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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Methylome profiling of young adults with depression supports a link with immune response and psoriasis

Fig. 3

Verification of methylation differences at psoriasis targets. a Top: genomic map indicating the region around the LCE3A gene. Tracks showing locations of array probes and probes showing differential methylation are as in Fig. 2. The location of the pyrosequencing assay (Pyro) upstream of the first exon of LCE3A is also shown. Genomic coordinates are as indicated. Bottom: Table comparing methylation levels as % at the CpG site covered both by an EPIC array probe and the pyroassay, which showed good agreement. b Top: genomic map showing the region on chr17 containing the MIR4520A/B locus (aka RefSeq MIR4520-1 and -2) and neighbouring genes. Tracks and key are as in a above. Bottom: Table comparing methylation at the CpG covered both by the array and the pyroassay, which were again concordant

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Clinical Epigenetics

ISSN: 1868-7083

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