From: Effect of short-term prescription opioids on DNA methylation of the OPRM1 promoter
Cell types | Cell proportions by visit (mean ± SD) | Pearson r with reference-based estimates | ||||
---|---|---|---|---|---|---|
Visit 1 | Visit 2 | Visit 3 | Visit p val | Lymphocytes | Granulocytes | |
Reference-free estimates | ||||||
Cell 1 | 0.60 ± 0.28 | 0.74 ± 0.23 | 0.47 ± 0.32 | F2,86 = 6.6, 0.002 | − 0.96 | 0.95 |
Cell 2 | 0.13 ± 0.13 | 0.10 ± 0.10 | 0.17 ± 0.15 | ns | 0.51 | − 0.47 |
Cell 3 | 0.21 ± 0.20 | 0.12 ± 0.18 | 0.22 ± 0.19 | ns | 0.43 | − 0.40 |
Cell 4 | 0.07 ± 0.18 | 0.03 ± 0.08 | 0.14 ± 0.23 | F2,86 = 2.7, 0.07 | 0.77 | − 0.81 |
Granulocytes | 0.71 ± 0.14 | 0.77 ± 0.10 | 0.64 ± 0.18 | F2,86 = 6.1, 0.003 | ||
Lymphocytes | 0.27 ± 0.12 | 0.21 ± 0.09 | 0.33 ± 0.15 | F2,86 = 6.6, 0.002 |