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Table 2 Reference-free and reference-based estimates of cellular proportions

From: Effect of short-term prescription opioids on DNA methylation of the OPRM1 promoter

Cell types

Cell proportions by visit (mean ± SD)

Pearson r with reference-based estimates

Visit 1

Visit 2

Visit 3

Visit p val

Lymphocytes

Granulocytes

Reference-free estimates

Cell 1

0.60 ± 0.28

0.74 ± 0.23

0.47 ± 0.32

F2,86 = 6.6, 0.002

− 0.96

0.95

Cell 2

0.13 ± 0.13

0.10 ± 0.10

0.17 ± 0.15

ns

0.51

− 0.47

Cell 3

0.21 ± 0.20

0.12 ± 0.18

0.22 ± 0.19

ns

0.43

− 0.40

Cell 4

0.07 ± 0.18

0.03 ± 0.08

0.14 ± 0.23

F2,86 = 2.7, 0.07

0.77

− 0.81

Granulocytes

0.71 ± 0.14

0.77 ± 0.10

0.64 ± 0.18

F2,86 = 6.1, 0.003

  

Lymphocytes

0.27 ± 0.12

0.21 ± 0.09

0.33 ± 0.15

F2,86 = 6.6, 0.002