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Fig. 7 | Clinical Epigenetics

Fig. 7

From: BTB/POZ zinc finger protein ZBTB16 inhibits breast cancer proliferation and metastasis through upregulating ZBTB28 and antagonizing BCL6/ZBTB27

Fig. 7

ZBTB16 forms heterodimer with ZBTB28 and BCL6, respectively, and upregulating ZBTB28 and antagonizing BCL6. a Co-IP outcome revealed the binding between BCL6, ZBTB28, and ZBTB16. b Cell viability in si-ZBTB28 or BCL6 overexpression group compared to si-control or vector group in vector-BT549 cell and ZBTB16-BT549 cell by CCK8 assay. c, d Cell migration and invasion ability in si-ZBTB28 or BCL6 overexpression group compared to si-control or vector group in vector-BT549 cell and ZBTB16-BT549 cell by Transwell assay. p value was assessed by t test. **p < 0.01; ***p < 0.001

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Clinical Epigenetics

ISSN: 1868-7083

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