Fig. 5

ZBTB16 suppresses xenograft breast tumor growth in nude mice. a Images of human BrCa tumor xenograft. Red and black arrows indicated empty vector control and ZBTB16-overexpressing tumors. b Tumor tissues from empty vector control and ZBTB16-overexpressing tumors (n = 6). c Growth curve of xenograft tumors. Tumor volume was calculated from tumor length and width, measured every two days. p value was assessed by t test. d Tumor weight measurements from empty vector control and ZBTB16-overexpressing tumors (n = 6). p value was assessed by t test. **p < 0.01. e Immunohistochemistry (IHC) and HE staining were used to evaluate the proliferation and nuclear fragmentation levels in nude mouse tissues