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Fig. 2 | Clinical Epigenetics

Fig. 2

From: BTB/POZ zinc finger protein ZBTB16 inhibits breast cancer proliferation and metastasis through upregulating ZBTB28 and antagonizing BCL6/ZBTB27

Fig. 2

Methylation and demethylation of ZBTB16 in breast cancer cells and tissues. aZBTB16 expression and methylation status in breast cancer cell lines. b The specificity of methylated primers was confirmed by not-bisulfite DNA. c Detection of ZBTB16 expression by RT-PCR before and after Aza treatment in breast tumor cells. d, e Methylation and unmethylation level before and after drug treatment in breast cancer cell lines. Methylation and demethylation were confirmed by quantitative methylation-specific PCR (qMSP). **p < 0.01; ***p < 0.001

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Clinical Epigenetics

ISSN: 1868-7083

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