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Fig. 1 | Clinical Epigenetics

Fig. 1

From: BTB/POZ zinc finger protein ZBTB16 inhibits breast cancer proliferation and metastasis through upregulating ZBTB28 and antagonizing BCL6/ZBTB27

Fig. 1

Expression and methylation of ZBTB16 in database. a The expression of ZBTB16 in 1041 breast tumor specimens and 112 normal breast tissue samples in TCGA. p value was assessed by Mann-Whitney U test. b The methylation status of ZBTB16 in 735 breast cancer specimens and 92 normal breast tissue samples in TCGA. p value was assessed by Mann-Whitney U test. c The expression of ZBTB16 in triple-negative breast cancer (TNBC) and basal-like breast cancer (n = 243) and not basal-like BrCa and not TNBC group (n = 3539). dZBTB16 expression in 77 pairs of breast cancer specimens and normal breast tissues in MethCH. e, f The expression and methylation level of ZBTB16 in 10 breast cancer tissues compared with paired non-cancerous breast tissues. g The higher ZBTB16 expression was association with better patient survival detected in the Kaplan-Meier Plotter dataset

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