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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression

Fig. 2

Genome-wide H3K4me1 profiling reveals differences between KMT2C deficient MSI CRC cell lines HCT116 and RKO. a–b H3K4me1 enrichment at a intestinal and b ubiquitous enhancers (**P < 0.01, ***P < 0.001). Dashed line marks 0. c Genome browser shot showing H3K4me1 ChIP-seq enrichment across human enhancers (gray dashed boxes), including an intestinal enhancer (black dashed box)

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Clinical Epigenetics

ISSN: 1868-7083

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