Fig. 3

EZH2/Lat1 positive feedback loop promotes the generation of SAM. EZH2 derepresses Lat1 expression and promotes the generation of SAM through direct promoter binding and subsequent transcriptional repression of RXRα
EZH2/Lat1 positive feedback loop promotes the generation of SAM. EZH2 derepresses Lat1 expression and promotes the generation of SAM through direct promoter binding and subsequent transcriptional repression of RXRα