Novel visualized quantitative epigenetic imprinted gene biomarkers diagnose the malignancy of ten cancer types

Clinical Epigenetics

Table 1 Sources of tumor cases for cancer-specific diagnostic model building in this study

Tissue type	Case numbers		Hospitals	IRB/IEC number
Tissue type	Benign*	Malignant	Hospitals	IRB/IEC number
Bladder	31	60	Shanghai Changhai Hospital	CHEC2019-029
Breast	26	61	Shanghai Changzhen Hospital	2018SL015
Colorectal	16	42	Shanghai Changzhen Hospital	2018SL015
Esophagus	18	41	Shanghai Changzhen Hospital	2018SL015
Gastric	18	42	Shanghai Changzhen Hospital	2018SL015
Lung	26	154	Shanghai Changzhen Hospital; Shanghai Institute of Respiratory Diseases, Shanghai Zhongshan Hospital	2018SL015, 2017-035R
Pancreatic	21	44	Shanghai Changzhen Hospital	2018SL015
Prostate	17	45	Shanghai Changzhen Hospital	2018SL015
Skin	13	38	Institute of Dermatology, Chinese Academy of Medical Sciences	2018-LKS-014
Thyroid	24	127	Jiangsu Jiangyuan Hospital, Shanghai Tenth People’s Hospital	YL201811, SHSY-IEC-4.1/19-6/01
Totals	204	654

*Benign samples were non-cancerous tissues from patients with benign lesions and used as negative control. Normal samples for gene screening were obtained adjacent to the benign lesions

ISSN: 1868-7083