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Table 2 Cox proportional hazard model of clinical parameters and TMEM240 mRNA expression level associated with Taiwan CRC patients

From: Hypermethylation and decreased expression of TMEM240 are potential early-onset biomarkers for colorectal cancer detection, poor prognosis, and early recurrence prediction

 Multivariate analysis 
VariableHR95% CIp value
LowerUpper
Overall survival
 Age0.2910.0511.6670.166
 Sex0.3080.0541.7400.182
 Stage4.7021.69513.0410.003
 Location2.9700.9858.9510.053
 Differentiation0.5990.03011.8970.737
 DNA methylation1.0051.0011.0100.028
 mRNA expression0.1960.0550.7040.012
Cancer specific survival
 Age0.1980.0251.5840.127
 Sex0.2450.0351.7180.157
 Stage7.6582.08328.1610.002
 Location4.0551.25713.0830.019
 Differentiation0.4630.01712.3070.646
 DNA methylation1.0061.0011.0110.025
 mRNA expression0.1420.0350.5870.007
Recurrence-free survival
 Age0.3600.0881.4730.155
 Sex0.3580.0951.3450.128
 Stage9.3853.24927.112< 0.000
 Location2.3380.9415.8090.067
 Differentiation0.8730.1435.3380.883
 DNA methylation1.0041.0001.0080.045
 mRNA expression0.2890.1000.8370.022