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Table 4 Delivery CRP and newborn DNA methylation in EAGeR

From: Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis

CpG

Beta

SE

p value

FDR p value

chr

pos

Gene name

Relation to island**

cg13138089

0.152

0.01988

2.11E−14

1.73E−08

2

233251770

ECEL1P2

Island

cg23289135

− 0.1253

0.01731

4.63E−13

1.90E−07

17

6182962

 

OpenSea

cg02323356

0.05283

0.008898

2.89E−09

0.00065

2

220313153

SPEG

Island

cg18875674

− 0.07196

0.01215

3.19E−09

0.00065

11

73026651

ARHGEF17

OpenSea

cg13558754

0.09236

0.01572

4.22E−09

0.00069

19

36247867

HSPB6; PROSER3

Island

cg16426346

− 0.09836

0.01706

8.14E−09

0.0011

6

1377047

 

N_Shore

cg20789824

− 0.02913

0.005279

3.42E−08

0.004

9

127562861

OLFML2A

OpenSea

cg17990365

− 0.04933

0.009036

4.79E−08

0.0049

11

319718

IFITM3

S_Shore

cg10884341

0.02292

0.004233

6.16E−08

0.0056

2

198365065

HSPE1

Island

cg20264732

0.02438

0.004544

8.05E−08

0.0066

16

68269763

ESRP2

Island

cg19013417

− 0.02286

0.004313

1.17E−07

0.0087

X

6146809

NLGN4X

S_Shore

cg19922333

− 0.04085

0.007806

1.66E−07

0.011

2

218253142

DIRC3

OpenSea

cg24340661

− 0.02255

0.004367

2.43E−07

0.012

1

166944531

MAEL; ILDR2

N_Shore

cg17238334

− 0.03159

0.00611

2.33E−07

0.012

5

71920983

LINC02056

OpenSea

cg23200634

− 0.09106

0.01763

2.39E−07

0.012

11

68709832

IGHMBP2

OpenSea

cg04415152*

0.03967

0.00764

2.08E−07

0.012

11

119383197

USP2-AS1

OpenSea

cg12615852

− 0.06756

0.01297

1.92E−07

0.0126

14

106330121

 

N_Shelf

cg12499872

0.06191

0.0121

3.09E−07

0.014

16

58019893

TEPP

Island

cg02660803

− 0.09608

0.01885

3.44E−07

0.015

X

91033070

PCDH11X

N_Shore

cg23133011

0.03135

0.006176

3.84E−07

0.016

11

122847242

BSX

N_Shore

cg25460807

0.04084

0.008097

4.55E−07

0.018

8

21908022

DMTN

S_Shelf

cg18449964

0.03482

0.006925

4.94E−07

0.018

18

72917101

ZADH2

Island

cg25389127

− 0.01482

0.002998

7.62E−07

0.027

X

8700496

ANOS1

Island

cg22876643

0.03535

0.007197

9.06E−07

0.03

1

68962318

DEPDC1

Island

cg04136921

− 0.05492

0.01121

9.67E−07

0.03

11

5626314

TRIM6; TRIM6-TRIM34

OpenSea

cg26354128

0.0325

0.006636

9.72E−07

0.03

14

93897195

UNC79

Island

cg19766763*

0.0307

0.006247

8.93E−07

0.03

18

61604237

SERPINB10

Island

cg19561181*

− 0.05247

0.0108

1.17E−06

0.03

20

56794558

ANKRD60

OpenSea

cg10235275*

0.03552

0.007398

1.58E−06

0.04

10

65225544

JMJD1C

Island

cg09689461*

0.0601

0.0126

1.84E−06

0.048

1

163130728

LOC101928404; RGS5

OpenSea

cg03305585

0.0339

0.007105

1.83E−06

0.048

7

37805796

 

OpenSea

cg21542650*

0.03161

0.00663

1.87E−06

0.048

12

2903593

FKBP4

Island

cg18973939

0.03444

0.007235

1.94E−06

0.048204347

1

16164122

FLJ37453

Island

  1. Model 3 adjusted for maternal age, smoking status, income, pre-pregnancy BMI, plate, and cell count distribution (as estimated in Gervin et al. [22])
  2. Asterisk (*) indicates CpG not previously identified in previous crude models or model 1 adjusting for cell type using Balkulski et al. [21]
  3. Double asterisks (**) as defined by Illumina [23]