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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Genome-wide DNA methylation profiles of low- and high-grade adenoma reveals potential biomarkers for early detection of colorectal carcinoma

Fig. 4

DNA methylation ADHFE1 and ACSS3 in normal, adenoma, and cancer. a Pathway of ethanol degradation II [26]. b Relationship between DNA methylation and gene expression of ADHFE1. c Relationship between DNA methylation and gene expression of ACSS3. d Left panel is identification of cutoff where the X axis is sample number of classification error; right panel is DNA methylation of ADHFE1 in normal, adenoma, and cancer samples. e Heatmap of sites within ADHFE1 promoter in normal, adenoma, and cancer samples. f ROC of the prediction of ADHFE1 for colorectal adenoma and cancer. g DNA methylation of ACSS3 in normal, adenoma, and cancer samples

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