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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Genome-wide DNA methylation profiles of low- and high-grade adenoma reveals potential biomarkers for early detection of colorectal carcinoma

Fig. 3

Hyper-methylated CpG sites showed better diagnostic performance than the hypo-methylated pattern. a Cluster analysis based on hyper-DMSs among normal, adenoma, and cancer samples. b Cluster analysis based on hypo-DMSs among normal, adenoma, and cancer samples. c Random forest prediction performance based on hyper- and hypo-DMSs. d Neural network prediction performance based on hyper- and hypo-DMSs. e t-SNE analysis highlights the data structure and sample relationship based on hyper-DMSs. f t-SNE analysis highlights the data structure and sample relationship based on hypo-DMSs. g Average methylation level of hyper- and hypo-DMSs. h ROC curve of hyper-mBV and hypo-mBV

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Clinical Epigenetics

ISSN: 1868-7083

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