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Table 1 Baseline descriptive statistics of included participants (N = 364)

From: Epigenetic prediction of complex traits and mortality in a cohort of individuals with oropharyngeal cancer

 

Alive (N = 273)

Dead (N = 91)

 

Characteristic

N

Frequency

N

Frequency

P value

Gender

 Male

209

76.6%

75

82.4%

0.242

 Female

64

23.4%

16

17.6%

 

Age at enrolment

 < 44

20

7.3%

3

3.3%

0.016

 45 to 54

83

30.4%

22

24.2%

 

 55 to 64

113

41.4%

34

37.4%

 

 65 to 74

48

17.6%

22

24.2%

 

 75 +

9

3.3%

10

11.0%

 

TNM stage

 Low (I–II)

39

14.3%

8

8.8%

0.176

 High (III–IV)

234

85.7%

83

91.2%

 

HPV status

 Negative

61

22.3%

48

52.7%

< 0.001

 Positive

212

77.7%

43

47.3%

 

BMI group

 Not overweight

73

38.0%

31

55.4%

0.021

 Overweight or obese

119

62.0%

25

44.6%

 

Comorbiditya

 None

164

60.1%

34

37.4%

< 0.001

 Mild

73

26.7%

29

31.9%

 

 Moderate/severe

36

13.2%

28

30.8%

 

Education level

 School education

116

42.5%

45

49.5%

0.470

 College

111

40.7%

34

37.4%

 

 Degree

46

16.8%

12

13.2%

 

Self-reported smoking status

 Never

96

35.2%

11

12.1%

< 0.001

 Former

140

51.3%

49

53.8%

 

 Current

37

13.6%

31

34.1%

 

Self-reported alcohol intake

 Non-drinker

75

27.5%

22

24.2%

0.119

 Moderate

68

24.9%

15

16.5%

 

 Hazardous-harmful

130

47.6%

54

59.3%

 
  1. BMI body mass index, HPV human papillomavirus, N number.aComorbidity was defined using the Adult Comorbidity Evaluation-27 (ACE-27) index [37]. For the purposes of analysis, moderate and severe comorbidity groups were combined