TY - JOUR AU - Relton, C. L. AU - Hartwig, F. P. AU - Davey, S. G. PY - 2015 DA - 2015// TI - From stem cells to the law courts: DNA methylation, the forensic epigenome and the possibility of a biosocial archive JO - Int J Epidemiol VL - 44 UR - https://doi.org/10.1093/ije/dyv198 DO - 10.1093/ije/dyv198 ID - Relton2015 ER - TY - JOUR AU - Philibert, R. AU - Hollenbeck, N. AU - Andersen, E. AU - Osborn, T. AU - Gerrard, M. AU - Gibbons, F. X. PY - 2015 DA - 2015// TI - A quantitative epigenetic approach for the assessment of cigarette consumption JO - Front Psychol VL - 6 UR - https://doi.org/10.3389/fpsyg.2015.00656 DO - 10.3389/fpsyg.2015.00656 ID - Philibert2015 ER - TY - JOUR AU - Zhang, Y. AU - Elgizouli, M. AU - Schottker, B. AU - Holleczek, B. AU - Nieters, A. AU - Brenner, H. PY - 2016 DA - 2016// TI - Smoking-associated DNA methylation markers predict lung cancer incidence JO - Clin Epigenetics VL - 8 UR - https://doi.org/10.1186/s13148-016-0292-4 DO - 10.1186/s13148-016-0292-4 ID - Zhang2016 ER - TY - JOUR AU - McCartney, D. L. AU - Hillary, R. F. AU - Stevenson, A. J. AU - Ritchie, S. J. AU - Walker, R. M. AU - Zhang, Q. PY - 2018 DA - 2018// TI - Epigenetic prediction of complex traits and death JO - Genome Biol VL - 19 UR - https://doi.org/10.1186/s13059-018-1514-1 DO - 10.1186/s13059-018-1514-1 ID - McCartney2018 ER - TY - JOUR AU - Bojesen, S. E. AU - Timpson, N. AU - Relton, C. AU - Davey Smith, G. AU - Nordestgaard, B. G. PY - 2017 DA - 2017// TI - AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality JO - Thorax VL - 72 UR - https://doi.org/10.1136/thoraxjnl-2016-208789 DO - 10.1136/thoraxjnl-2016-208789 ID - Bojesen2017 ER - TY - BOOK AU - Guida, F. AU - Nost, T. H. AU - Relton, C. AU - Brennan, P. AU - Sandanger, T. M. AU - Chadeau-Hyam, M. PY - 2018 DA - 2018// TI - Lung cancer risk prediction using DNA methylation markers Cancer Research ID - Guida2018 ER - TY - JOUR AU - Zhang, Y. AU - Breitling, L. P. AU - Balavarca, Y. AU - Holleczek, B. AU - Schottker, B. AU - Brenner, H. PY - 2016 DA - 2016// TI - Comparison and combination of blood DNA methylation at smoking-associated genes and at lung cancer-related genes in prediction of lung cancer mortality JO - Int J Cancer VL - 139 UR - https://doi.org/10.1002/ijc.30374 DO - 10.1002/ijc.30374 ID - Zhang2016 ER - TY - STD TI - Zhang Y, Wilson R, Heiss J, Breitling LP, Saum KU, Schottker B, et al. DNA methylation signatures in peripheral blood strongly predict all-cause mortality. Nature Commun. 2017;8. ID - ref8 ER - TY - STD TI - Ness AR, Waylen A, Hurley K, Jeffreys M, Penfold C, Pring M, et al. Establishing a large prospective clinical cohort in people with head and neck cancer as a biomedical resource: head and neck 5000. Bmc Cancer. 2014;14. ID - ref9 ER - TY - JOUR AU - Sharp, L. AU - McDevitt, J. AU - Carsin, A. E. AU - Brown, C. AU - Comber, H. PY - 2014 DA - 2014// TI - Smoking at diagnosis is an independent prognostic factor for cancer-specific survival in head and neck cancer: findings from a large, population-based study JO - Cancer Epidemiol Biomarkers Prev VL - 23 UR - https://doi.org/10.1158/1055-9965.EPI-14-0311 DO - 10.1158/1055-9965.EPI-14-0311 ID - Sharp2014 ER - TY - JOUR AU - Duffy, S. A. AU - Ronis, D. L. AU - McLean, S. AU - Fowler, K. E. AU - Gruber, S. B. AU - Wolf, G. T. PY - 2009 DA - 2009// TI - Pretreatment health behaviors predict survival among patients with head and neck squamous cell carcinoma JO - J Clin Oncol VL - 27 UR - https://doi.org/10.1200/JCO.2008.18.2188 DO - 10.1200/JCO.2008.18.2188 ID - Duffy2009 ER - TY - JOUR AU - Hilgert, E. AU - Bergmann, C. AU - Fichtner, A. AU - Gires, O. AU - Issing, W. PY - 2009 DA - 2009// TI - Tobacco abuse relates to significantly reduced survival of patients with oropharyngeal carcinomas JO - Eur J Cancer Prev VL - 18 UR - https://doi.org/10.1097/CEJ.0b013e32831012a4 DO - 10.1097/CEJ.0b013e32831012a4 ID - Hilgert2009 ER - TY - JOUR AU - Mayne, S. T. AU - Cartmel, B. AU - Kirsh, V. AU - Goodwin, W. J. PY - 2009 DA - 2009// TI - Alcohol and tobacco use prediagnosis and postdiagnosis, and survival in a cohort of patients with early stage cancers of the oral cavity, pharynx, and larynx JO - Cancer Epidemiol Biomarkers Prev VL - 18 UR - https://doi.org/10.1158/1055-9965.EPI-09-0944 DO - 10.1158/1055-9965.EPI-09-0944 ID - Mayne2009 ER - TY - JOUR AU - Gama, R. R. AU - Song, Y. AU - Zhang, Q. AU - Brown, M. C. AU - Wang, J. AU - Habbous, S. PY - 2017 DA - 2017// TI - Body mass index and prognosis in patients with head and neck cancer JO - Head Neck VL - 39 UR - https://doi.org/10.1002/hed.24760 DO - 10.1002/hed.24760 ID - Gama2017 ER - TY - JOUR AU - Hollander, D. AU - Kampman, E. AU - Herpen, C. M. PY - 2015 DA - 2015// TI - Pretreatment body mass index and head and neck cancer outcome: a review of the literature JO - Crit Rev Oncol Hematol VL - 96 UR - https://doi.org/10.1016/j.critrevonc.2015.06.002 DO - 10.1016/j.critrevonc.2015.06.002 ID - Hollander2015 ER - TY - JOUR AU - Choi, S. H. AU - Terrell, J. E. AU - Fowler, K. E. AU - McLean, S. A. AU - Ghanem, T. AU - Wolf, G. T. PY - 2016 DA - 2016// TI - Socioeconomic and other demographic disparities predicting survival among head and neck cancer patients JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0149886 DO - 10.1371/journal.pone.0149886 ID - Choi2016 ER - TY - STD TI - Banos DT, McCartney DL, Battram T, Hemani G, Walker RM, Morris SW, et al. Bayesian reassessment of the epigenetic architecture of complex traits. 2018:450288. ID - ref17 ER - TY - JOUR AU - Liu, C. AU - Marioni, R. E. AU - Hedman, A. K. AU - Pfeiffer, L. AU - Tsai, P. C. AU - Reynolds, L. M. PY - 2018 DA - 2018// TI - A DNA methylation biomarker of alcohol consumption JO - Mol Psychiatry VL - 23 UR - https://doi.org/10.1038/mp.2016.192 DO - 10.1038/mp.2016.192 ID - Liu2018 ER - TY - JOUR AU - Joehanes, R. AU - Just, A. C. AU - Marioni, R. E. AU - Pilling, L. C. AU - Reynolds, L. M. AU - Mandaviya, P. R. PY - 2016 DA - 2016// TI - Epigenetic signatures of cigarette smoking JO - Circ Cardiovasc Genet VL - 9 UR - https://doi.org/10.1161/CIRCGENETICS.116.001506 DO - 10.1161/CIRCGENETICS.116.001506 ID - Joehanes2016 ER - TY - JOUR AU - Zhang, Y. AU - Florath, I. AU - Saum, K. U. AU - Brenner, H. PY - 2016 DA - 2016// TI - Self-reported smoking, serum cotinine, and blood DNA methylation JO - Environ Res VL - 146 UR - https://doi.org/10.1016/j.envres.2016.01.026 DO - 10.1016/j.envres.2016.01.026 ID - Zhang2016 ER - TY - JOUR AU - Peterson, L. A. AU - Bellile, E. L. AU - Wolf, G. T. AU - Virani, S. AU - Shuman, A. G. AU - Taylor, J. M. PY - 2016 DA - 2016// TI - Cigarette use, comorbidities, and prognosis in a prospective head and neck squamous cell carcinoma population JO - Head Neck VL - 38 UR - https://doi.org/10.1002/hed.24515 DO - 10.1002/hed.24515 ID - Peterson2016 ER - TY - JOUR AU - Ang, K. K. AU - Harris, J. AU - Wheeler, R. AU - Weber, R. AU - Rosenthal, D. I. AU - Nguyen-Tan, P. F. PY - 2010 DA - 2010// TI - Human papillomavirus and survival of patients with oropharyngeal cancer JO - N Engl J Med VL - 363 UR - https://doi.org/10.1056/NEJMoa0912217 DO - 10.1056/NEJMoa0912217 ID - Ang2010 ER - TY - JOUR AU - Imhoff, L. C. AU - Kranenburg, G. G. AU - Macco, S. AU - Nijman, N. L. AU - Overbeeke, E. J. AU - Wegner, I. PY - 2016 DA - 2016// TI - Prognostic value of continued smoking on survival and recurrence rates in patients with head and neck cancer: a systematic review JO - Head Neck VL - 38 UR - https://doi.org/10.1002/hed.24082 DO - 10.1002/hed.24082 ID - Imhoff2016 ER - TY - JOUR AU - Beynon, R. A. AU - Lang, S. AU - Schimansky, S. AU - Penfold, C. M. AU - Waylen, A. AU - Thomas, S. J. PY - 2018 DA - 2018// TI - Tobacco smoking and alcohol drinking at diagnosis of head and neck cancer and all-cause mortality: results from head and neck 5000, a prospective observational cohort of people with head and neck cancer JO - Int J Cancer VL - 143 UR - https://doi.org/10.1002/ijc.31416 DO - 10.1002/ijc.31416 ID - Beynon2018 ER - TY - JOUR AU - Beesley, L. J. AU - Hawkins, P. G. AU - Amlani, L. M. AU - Bellile, E. L. AU - Casper, K. A. AU - Chinn, S. B. PY - 2019 DA - 2019// TI - Individualized survival prediction for patients with oropharyngeal cancer in the human papillomavirus era JO - Cancer VL - 125 UR - https://doi.org/10.1002/cncr.31739 DO - 10.1002/cncr.31739 ID - Beesley2019 ER - TY - JOUR AU - Rios Velazquez, E. AU - Hoebers, F. AU - Aerts, H. J. AU - Rietbergen, M. M. AU - Brakenhoff, R. H. AU - Leemans, R. C. PY - 2014 DA - 2014// TI - Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging JO - Radiother Oncol VL - 113 UR - https://doi.org/10.1016/j.radonc.2014.09.005 DO - 10.1016/j.radonc.2014.09.005 ID - Rios Velazquez2014 ER - TY - JOUR AU - Fakhry, C. AU - Zhang, Q. AU - Nguyen-Tan, P. F. AU - Rosenthal, D. I. AU - Weber, R. S. AU - Lambert, L. PY - 2017 DA - 2017// TI - Development and validation of nomograms predictive of overall and progression-free survival in patients with oropharyngeal cancer JO - J Clin Oncol VL - 35 UR - https://doi.org/10.1200/JCO.2016.72.0748 DO - 10.1200/JCO.2016.72.0748 ID - Fakhry2017 ER - TY - JOUR AU - Larsen, C. G. AU - Jensen, D. H. AU - Carlander, A. F. AU - Kiss, K. AU - Andersen, L. AU - Olsen, C. H. PY - 2016 DA - 2016// TI - Novel nomograms for survival and progression in HPV+ and HPV- oropharyngeal cancer: a population-based study of 1542 consecutive patients JO - Oncotarget VL - 7 UR - https://doi.org/10.18632/oncotarget.12335 DO - 10.18632/oncotarget.12335 ID - Larsen2016 ER - TY - STD TI - Centre EM. Prediction of survival in patients with HNSCC [Available from: https://erasmusmc.thirdwave.nl/model/. UR - https://erasmusmc.thirdwave.nl/model/ ID - ref29 ER - TY - STD TI - Little RJ, Rubin DB. Statistical analysis with missing data. New Jersey: Wiley; 2019. ID - ref30 ER - TY - JOUR AU - Hughes, R. A. AU - Heron, J. AU - Sterne, J. A. C. AU - Tilling, K. PY - 2019 DA - 2019// TI - Accounting for missing data in statistical analyses: multiple imputation is not always the answer JO - Int J Epidemiol VL - 48 UR - https://doi.org/10.1093/ije/dyz032 DO - 10.1093/ije/dyz032 ID - Hughes2019 ER - TY - JOUR AU - Smith Sehdev, A. E. AU - Hutchins, G. M. PY - 2001 DA - 2001// TI - Problems with proper completion and accuracy of the cause-of-death statement JO - Arch Intern Med VL - 161 UR - https://doi.org/10.1001/archinte.161.2.277 DO - 10.1001/archinte.161.2.277 ID - Smith Sehdev2001 ER - TY - JOUR AU - Polednak, A. P. PY - 2014 DA - 2014// TI - Inaccuracies in oral cavity–pharynx cancer coded as the underlying cause of death on U.S. death certificates, and trends in mortality rates (1999–2010) JO - Oral Oncology VL - 50 UR - https://doi.org/10.1016/j.oraloncology.2014.04.012 DO - 10.1016/j.oraloncology.2014.04.012 ID - Polednak2014 ER - TY - JOUR AU - Gao, X. AU - Jia, M. AU - Zhang, Y. AU - Breitling, L. P. AU - Brenner, H. PY - 2015 DA - 2015// TI - DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies JO - Clin Epigenet VL - 7 UR - https://doi.org/10.1186/s13148-015-0148-3 DO - 10.1186/s13148-015-0148-3 ID - Gao2015 ER - TY - JOUR AU - Vadigepalli, R. AU - Hoek, J. B. PY - 2018 DA - 2018// TI - Introduction to the virtual issue alcohol and epigenetic regulation: do the products of alcohol metabolism drive epigenetic control of gene expression in alcohol-related disorders? JO - Alcohol Clin Experiment Res VL - 42 UR - https://doi.org/10.1111/acer.13630 DO - 10.1111/acer.13630 ID - Vadigepalli2018 ER - TY - JOUR AU - Russo, D. AU - Merolla, F. AU - Varricchio, S. AU - Salzano, G. AU - Zarrilli, G. AU - Mascolo, M. PY - 2018 DA - 2018// TI - Epigenetics of oral and oropharyngeal cancers JO - Biomed Rep VL - 9 ID - Russo2018 ER - TY - JOUR AU - Ness, A. R. AU - Waylen, A. AU - Hurley, K. AU - Jeffreys, M. AU - Penfold, C. AU - Pring, M. PY - 2016 DA - 2016// TI - Recruitment, response rates and characteristics of 5511 people enrolled in a prospective clinical cohort study: head and neck 5000 JO - Clin Otolaryngol VL - 41 UR - https://doi.org/10.1111/coa.12548 DO - 10.1111/coa.12548 ID - Ness2016 ER - TY - JOUR AU - Lesseur, C. AU - Diergaarde, B. AU - Olshan, A. F. AU - Wunsch-Filho, V. AU - Ness, A. R. AU - Liu, G. PY - 2016 DA - 2016// TI - Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer JO - Nat Genet VL - 48 UR - https://doi.org/10.1038/ng.3685 DO - 10.1038/ng.3685 ID - Lesseur2016 ER - TY - JOUR AU - Bradley, P. J. AU - Zutshi, B. AU - Nutting, C. M. PY - 2005 DA - 2005// TI - An audit of clinical resources available for the care of head and neck cancer patients in England JO - Clin Oncol (R Coll Radiol) VL - 17 UR - https://doi.org/10.1016/j.clon.2005.07.015 DO - 10.1016/j.clon.2005.07.015 ID - Bradley2005 ER - TY - BOOK PY - 2016 DA - 2016// TI - International statistical classification of diseases and related health problems 10th revision ID - ref40 ER - TY - BOOK AU - Sobin, L. AU - Gospodarowicz, M. AU - Wittekind, C. PY - 2011 DA - 2011// TI - TNM Classification of malignant tumours, 7th edition: Wiley-Blackwell| ID - Sobin2011 ER - TY - STD TI - Adult Comorbidity Evaluation-27: NHS; 2018 [Available from: https://www.datadictionary.nhs.uk/data_dictionary/nhs_business_definitions/a/adult_comorbidity_evaluation_-_27_de.asp?shownav=1. UR - https://www.datadictionary.nhs.uk/data_dictionary/nhs_business_definitions/a/adult_comorbidity_evaluation_-_27_de.asp?shownav=1 ID - ref42 ER - TY - STD TI - Drummond C, Pilling S, Brown A, Copello A, Day E, Dyer M, et al. Alcohol use disorders: the NICE guideline on diagnosis, assessment and management of harmful drinking and alcohol dependence 2011. ID - ref43 ER - TY - STD TI - Min J, Hemani G, Davey Smith G, Relton CL, Suderman M. Meffil: efficient normalisation and analysis of very large DNA methylation samples. bioRxiv. 2017. ID - ref44 ER - TY - JOUR AU - Ambatipudi, S. AU - Langdon, R. AU - Richmond, R. C. AU - Suderman, M. AU - Koestler, D. C. AU - Kelsey, K. T. PY - 2018 DA - 2018// TI - DNA methylation derived systemic inflammation indices are associated with head and neck cancer development and survival JO - Oral Oncol VL - 85 UR - https://doi.org/10.1016/j.oraloncology.2018.08.021 DO - 10.1016/j.oraloncology.2018.08.021 ID - Ambatipudi2018 ER - TY - JOUR AU - Triche, T. J. AU - Weisenberger, D. J. AU - Berg, D. AU - Laird, P. W. AU - Siegmund, K. D. PY - 2013 DA - 2013// TI - Low-level processing of Illumina Infinium DNA Methylation BeadArrays JO - Nucleic Acids Res VL - 41 UR - https://doi.org/10.1093/nar/gkt090 DO - 10.1093/nar/gkt090 ID - Triche2013 ER - TY - JOUR AU - Fortin, J. P. AU - Triche, T. J. AU - Hansen, K. D. PY - 2017 DA - 2017// TI - Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfi JO - Bioinformatics VL - 33 ID - Fortin2017 ER - TY - JOUR AU - Houseman, E. A. AU - Accomando, W. P. AU - Koestler, D. C. AU - Christensen, B. C. AU - Marsit, C. J. AU - Nelson, H. H. PY - 2012 DA - 2012// TI - DNA methylation arrays as surrogate measures of cell mixture distribution JO - BMC Bioinformatics VL - 13 UR - https://doi.org/10.1186/1471-2105-13-86 DO - 10.1186/1471-2105-13-86 ID - Houseman2012 ER - TY - JOUR AU - Reinius, L. E. AU - Acevedo, N. AU - Joerink, M. AU - Pershagen, G. AU - Dahlen, S. E. AU - Greco, D. PY - 2012 DA - 2012// TI - Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0041361 DO - 10.1371/journal.pone.0041361 ID - Reinius2012 ER - TY - BOOK AU - Brierley, J. D. G. M. AU - Wittekind, C. PY - 2017 DA - 2017// TI - TNM classification of malignant tumours ID - Brierley2017 ER - TY - JOUR AU - Schimansky, S. AU - Lang, S. AU - Beynon, R. AU - Penfold, C. AU - Davies, A. AU - Waylen, A. PY - 2019 DA - 2019// TI - Association between comorbidity and survival in head and neck cancer: results from Head and Neck 5000 JO - Head Neck VL - 41 UR - https://doi.org/10.1002/hed.25543 DO - 10.1002/hed.25543 ID - Schimansky2019 ER - TY - JOUR AU - Sogaard, M. AU - Thomsen, R. W. AU - Bossen, K. S. AU - Sorensen, H. T. AU - Norgaard, M. PY - 2013 DA - 2013// TI - The impact of comorbidity on cancer survival: a review JO - Clin Epidemiol VL - 5 UR - https://doi.org/10.2147/CLEP.S47150 DO - 10.2147/CLEP.S47150 ID - Sogaard2013 ER - TY - JOUR AU - Royston, P. PY - 2009 DA - 2009// TI - Multiple imputation of missing values: further update of ice, with an emphasis on categorical variables JO - Stata J VL - 9 UR - https://doi.org/10.1177/1536867X0900900308 DO - 10.1177/1536867X0900900308 ID - Royston2009 ER - TY - JOUR AU - Rubin, D. B. AU - Schenker, N. PY - 1986 DA - 1986// TI - Multiple imputation for interval estimation from simple random samples with ignorable nonresponse JO - J Am Stat Assoc VL - 81 UR - https://doi.org/10.1080/01621459.1986.10478280 DO - 10.1080/01621459.1986.10478280 ID - Rubin1986 ER - TY - BOOK AU - Rubin, D. B. PY - 1987 DA - 1987// TI - Multiple imputation for nonresponse in surveys PB - Wiley CY - New York UR - https://doi.org/10.1002/9780470316696 DO - 10.1002/9780470316696 ID - Rubin1987 ER - TY - JOUR AU - Royston, P. AU - Carlin, J. B. AU - White, I. R. PY - 2009 DA - 2009// TI - Multiple imputation of missing values: new features for mim JO - Stata J VL - 9 UR - https://doi.org/10.1177/1536867X0900900205 DO - 10.1177/1536867X0900900205 ID - Royston2009 ER - TY - JOUR AU - Robin, X. AU - Turck, N. AU - Hainard, A. AU - Tiberti, N. AU - Lisacek, F. AU - Sanchez, J. C. PY - 2011 DA - 2011// TI - pROC: an open-source package for R and S+ to analyze and compare ROC curves JO - BMC Bioinformatics VL - 12 UR - https://doi.org/10.1186/1471-2105-12-77 DO - 10.1186/1471-2105-12-77 ID - Robin2011 ER - TY - JOUR AU - Hajian-Tilaki, K. PY - 2013 DA - 2013// TI - Receiver operating characteristic (ROC) curve analysis for medical diagnostic test evaluation JO - Caspian J Intern Med VL - 4 ID - Hajian-Tilaki2013 ER - TY - JOUR AU - DeLong, E. R. AU - DeLong, D. M. AU - Clarke-Pearson, D. L. PY - 1988 DA - 1988// TI - Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach JO - Biometrics VL - 44 UR - https://doi.org/10.2307/2531595 DO - 10.2307/2531595 ID - DeLong1988 ER -