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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Evaluation of a methylation classifier for predicting pre-cancer lesion among women with abnormal results between HPV16/18 and cytology

Fig. 2

S5 score distributions by histological diagnosis: no lesion, LSIL, HSIL, and cervical cancer (CC). No lesion vs HSIL (p < 0.001), no lesion vs CC (p < 0.001), LSIL vs HSIL (p < 0.001), LSIL vs CC (p < 0.001), and HSIL vs CC (p < 0.001). The middle line is the median; the Cuzick test for trend was significant (p < 0.001). The upper whisker extends to the largest point of the inter-quartile range from the upper quartile. The lower whisker extends to the smallest point of the inter-quartile range from the lower quartile. No lesion, histologically negative without squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; CC, cervical cancer

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