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Table 1 Characteristics of the study population

From: Adverse childhood experiences, DNA methylation age acceleration, and cortisol in UK children: a prospective population-based cohort study

Characteristics

Mean (SE) or % in girls

Mean (SE) or % in boys

P valuea

N

500

474

 

Chronological age

17.11 (0.05)

17.16 (0.05)

0.46

DNA methylation age acceleration (years)

− 0.24 (0.18)

0.25 (0.17)

0.05

Plasma cortisol (nmol/L)

522.54 (15.99)

465.85 (11.24)

< 0.01

Count of adverse childhood experiences

  

0.85

 None

21.5

22.0

 

 One

24.4

25.9

 

 Two or three

35.9

32.7

 

 Four or more

18.2

19.4

 

Individual adverse childhood experience exposure

   

 Bullying

14.4

17.1

0.26

 Emotional abuse

22.9

21.9

0.75

 Emotional neglect

14.6

16.9

0.34

 Parent mental health problem

52.7

47.2

0.13

 Parent convicted

13.1

11.6

0.60

 Parental separation

20.9

25.9

0.11

 Physical abuse

18.0

17.8

0.95

 Sexual abuse

4.9

2.0

0.05

 Household substance abuse

13.4

13.9

0.85

 Violence in household

21.3

21.9

0.85

  1. SE standard error
  2. aTwo-tailed P value