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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Adverse childhood experiences, DNA methylation age acceleration, and cortisol in UK children: a prospective population-based cohort study

Fig. 2

Cumulative exposure to adverse childhood experiences from age 0–14 years and DNA methylation age acceleration at age 17 years. DNAm AA, Horvath-estimated DNA methylation age acceleration; ACE, adverse childhood experiences. Scatter plots show mean differences in DNAm AA for each category of ACE exposure when compared to zero exposure to ACE. Whiskers show 95% confidence intervals. aAdjusted for white blood cell composition, smoking status, maternal body mass index, maternal smoking, maternal age at delivery, maternal depression, partner’s depression, mother’s highest education qualification, household’s highest socioeconomic class

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