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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Adipose stem cells from patients with Crohn’s disease show a distinctive DNA methylation pattern

Fig. 4

Gene expression of candidate genes obtained from differentially methylated regions between hASCs isolated from patients with active or inactive Crohn’s disease and control individuals. a Genes involved in immune system response: C2, IKBKE, IKBKG, LTBR, SPON2, CHID1, and TNFA. b Genes related to the regulation of metabolism: G6PD, FGF13, EBF3, and RIPK1. c Genes related to cell differentiation: EN1, WT1, FGF1, FGFR2, PRDM8, PRDM16, and DLX5. d Genes involved in development process: HOXB5, HOXB6 and SHROOM3. One-way analysis of variance with multiple comparisons corrected by Newman-Keuls test was used. *p < 0.05 versus control-hASCs; $p < 0.05 versus active CD-hASCs

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