Fig. 1
From: Adipose stem cells from patients with Crohn’s disease show a distinctive DNA methylation pattern
Exploratory data analysis. a Score plot of the first two principal components of the overall DNA methylation profiles, showing a discernable differentiation between patients with CD (blue circles) and healthy controls (red circles). b Heatmap showing the correlation data between the six main components and clinical parameters such as hospital, sex, age, body mass index [BMI], or disease. Each cell of the heatmap shows the Pearson correlation coefficient. Asterisk indicates significant correlation. c Percentage of differentially methylated positions (DMPs) of all the human DNA methylome distributed in three classes: unmethylated regions (UMR < 25% methylated CpGs); low-methylated regions (LMR < 25% methylated CpGs); and fully methylated regions (FMR > 50% methylated CpGs)