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Fig. 3 | Clinical Epigenetics

Fig. 3

From: SEPT9_v2, frequently silenced by promoter hypermethylation, exerts anti-tumor functions through inactivation of Wnt/β-catenin signaling pathway via miR92b-3p/FZD10 in nasopharyngeal carcinoma cells

Fig. 3

SEPT9_v2 inhibited NPC cell migration and invasion. a Stably transfected HONE1 and HNE1 cells in a wound healing assay at 0 and 24 h. Left: representative image. Right: distance of cell migration. b, c Transwell assay examined the migration and invasion of cells stably transfected with vector or SEPT9_v2. d The expression of MMP1 and MMP10 in the stably transfected cells detected by qPCR. MMP1, matrix metalloproteinase 1; MMP10, matrix metalloproteinase 10. All values are presented as the mean ± SD of at least three independent experiments. SD, standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001

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Clinical Epigenetics

ISSN: 1868-7083

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