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Table 6 Sensitivity, Specificity, PPV, and NPV at optimal cutoffs with AUC regarding tumor size (1.1–2 cm)

From: Ultrasensitive DNA hypermethylation detection using plasma for early detection of NSCLC: a study in Chinese patients with very small nodules

GeneSensitivitySpecificityPPVNPVAUC95% CI
CDO172%88%93%59%0.800.73–0.88
TAC170%70%83%52%0.690.60–0.79
SOX1765%93%95%55%0.820.75–0.89
HOXA761%77%85%48%0.720.63–0.81
CDO1, TAC1, SOX1773%93%96%62%0.910.87–0.97
CDO1, SOX17, HOXA774%93%96%63%0.920.87–0.96
  1. Cancer, n = 92; control, n = 43