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Table 4 Performance of gene methylation panel in the prediction of early stage lung cancer

From: Ultrasensitive DNA hypermethylation detection using plasma for early detection of NSCLC: a study in Chinese patients with very small nodules

GeneSensitivitySpecificityPPVNPVAUC95% CI
Clinical predictors alone81%47%75%56%0.700.65–0.79
Clinical predictors + CDO1, TAC1, SOX1793%63%83%82%0.900.86–0.93
Clinical Predictors + CDO1, SOX17, HOXA791%79%89%82%0.940.91–0.96
  1. AUC, area under the curve (in the ROC curves); 95% CI, 95 % confidence interval