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Table 3 Sensitivity, specificity, PPV, and NPV at optimal cutoffs with AUC

From: Ultrasensitive DNA hypermethylation detection using plasma for early detection of NSCLC: a study in Chinese patients with very small nodules

GeneSensitivitySpecificityPPVNPVAUC95% CI
CDO163%83%88%53%0.780.71–0.83
TAC168%70%81%52%0.710.64–0.78
SOX1768%86%90%57%0.820.76–0.87
HOXA755%87%89%50%0.730.67–0.80
HOXA964%49%71%41%0.560.48–0.64
GATA444%58%67%35%0.530.45–0.61
GATA543%63%70%36%0.520.44–0.60
PAX541%55%64%32%0.540.45–0.62
CDO1, TAC1, SOX1789%61%82%74%0.850.81–0.91
CDO1, SOX17, HOXA790%71%86%78%0.880.84–0.93