Table 3 Sensitivity, specificity, PPV, and NPV at optimal cutoffs with AUC
Gene | Sensitivity | Specificity | PPV | NPV | AUC | 95% CI |
|---|---|---|---|---|---|---|
CDO1 | 63% | 83% | 88% | 53% | 0.78 | 0.71–0.83 |
TAC1 | 68% | 70% | 81% | 52% | 0.71 | 0.64–0.78 |
SOX17 | 68% | 86% | 90% | 57% | 0.82 | 0.76–0.87 |
HOXA7 | 55% | 87% | 89% | 50% | 0.73 | 0.67–0.80 |
HOXA9 | 64% | 49% | 71% | 41% | 0.56 | 0.48–0.64 |
GATA4 | 44% | 58% | 67% | 35% | 0.53 | 0.45–0.61 |
GATA5 | 43% | 63% | 70% | 36% | 0.52 | 0.44–0.60 |
PAX5 | 41% | 55% | 64% | 32% | 0.54 | 0.45–0.62 |
CDO1, TAC1, SOX17 | 89% | 61% | 82% | 74% | 0.85 | 0.81–0.91 |
CDO1, SOX17, HOXA7 | 90% | 71% | 86% | 78% | 0.88 | 0.84–0.93 |