Table 1 Clinical characteristics of the patients
Patient characteristics | Cancer group (n = 163) | Control group (n = 83) | p value |
|---|---|---|---|
Age (year, mean ± SD) | 58.79 ± 9.11 | 52.45 ± 7.27 | 0.01 |
Gender (%) | |||
 Male | 84 (51.5%) | 52 (62.7%) | 0.32 |
 Female | 79 (48.5%) | 31 (37.3%) | |
Stage no. (%) | |||
 T1N0 | 102 (62.6%) | N/A | N/A |
 T2N0 | 61 (37.4%) | N/A | |
Histologic characteristics no. (%) | |||
 Adenocarcinoma | 139 (85.3%) | N/A | N/A |
 Squamous-cell | 22 (13.5%) | N/A | |
 NOS | 2 (1.2%) | N/A | |
 Granuloma | N/A | 35 (42.2%) | |
 Hamartoma | N/A | 10 (12.0%) | |
 Inflammation | N/A | 29 (34.9%) | |
 Fungal infection | N/A | 2 (2.4%) | |
 Other benign | N/A | 7 (8.5%) | |
Nodule size (cm, mean ± SD) | 1.78 ± 0.67 | 1.64 ± 0.73 | 0.33 |
 0–1.0 cm | 28 (17.2%) | 22 (26.5%) | 0.22 |
 1.1–2.0 cm | 92 (56.4%) | 43 (51.8%) | |
 2.1–3.0 cm | 43 (26.4%) | 18 (21.7%) | |
Pack-year (IQR) | 38 (10–150) | 35 (0.75–90) | 0.57 |
COPD no. (%) | 2 (1.2%) | 2 (2.4%) | 0.49 |
FEV1 (L, mean ± SD) | 2.32 ± 0.79 | 2.65 ± 0.70 | 0.29 |
FVC (L, mean ± SD) | 3.00 ± 1.02 | 3.42 ± 0.86 | 0.23 |
FEV1/FVC (%, mean ± SD) | 73.52 ± 18.53 | 76.76 ± 14.31 | 0.11 |