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Table 1 Clinical characteristics of the patients

From: Ultrasensitive DNA hypermethylation detection using plasma for early detection of NSCLC: a study in Chinese patients with very small nodules

Patient characteristicsCancer group (n = 163)Control group (n = 83)p value
Age (year, mean ± SD)58.79 ± 9.1152.45 ± 7.270.01
Gender (%)
 Male84 (51.5%)52 (62.7%)0.32
 Female79 (48.5%)31 (37.3%)
Stage no. (%)
 T1N0102 (62.6%)N/AN/A
 T2N061 (37.4%)N/A
Histologic characteristics no. (%)
 Adenocarcinoma139 (85.3%)N/AN/A
 Squamous-cell22 (13.5%)N/A
 NOS2 (1.2%)N/A
 GranulomaN/A35 (42.2%)
 HamartomaN/A10 (12.0%)
 InflammationN/A29 (34.9%)
 Fungal infectionN/A2 (2.4%)
 Other benignN/A7 (8.5%)
Nodule size (cm, mean ± SD)1.78 ± 0.671.64 ± 0.730.33
 0–1.0 cm28 (17.2%)22 (26.5%)0.22
 1.1–2.0 cm92 (56.4%)43 (51.8%)
 2.1–3.0 cm43 (26.4%)18 (21.7%)
Pack-year (IQR)38 (10–150)35 (0.75–90)0.57
COPD no. (%)2 (1.2%)2 (2.4%)0.49
FEV1 (L, mean ± SD)2.32 ± 0.792.65 ± 0.700.29
FVC (L, mean ± SD)3.00 ± 1.023.42 ± 0.860.23
FEV1/FVC (%, mean ± SD)73.52 ± 18.5376.76 ± 14.310.11
  1. COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; IQR, interquartile range