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Table 1 Participant characteristics at baseline

From: Platelet mitochondrial DNA methylation predicts future cardiovascular outcome in adults with overweight and obesity

Variable

All participants (n = 200)

CVD-free at the follow-up (n = 116)

CVD-developed at the follow-up (n = 84)

P value

Sex (n, %)

 Male

78 (39%)

44 (38%)

34 (40%)

0.716

 Female

122 (61%)

72 (62%)

50 (60%)

Age (mean, SD)

62.5, ± 10

61.7, ± 9.5

63.5, ± 10.6

0.210

BMI (mean, SD)

35.5, ± 5.1

35.4, ± 4.9

35.5, ± 5.4

0.936

BMI categorical (n, %)

 25.1–30.0 (overweight)

34 (17%)

22 (19%)

12 (14%)

0.762

 30.1–34.9 (obesity I)

62 (31%)

33 (28%)

29 (35%)

 > 35.1 (obesity II and III)

104 (52%)

61 (53%)

43 (51%)

Smoking status (n, %)

 Never

89 (45%)

53 (46%)

36 (43%)

0.859

 Former

91 (46%)

50 (43%)

41 (49%)

 Current

19 (10%)

13 (11%)

6 (7%)

Education, years of education (n, %)

 Primary school and other (< 5 years)

34 (17%)

18 (16%)

16 (19%)

0.297

 Secondary school and high school (< 13 years)

129 (65%)

76 (66%)

53 (63%)

 University degree (> 14 years)

32 (16%)

21 (18%)

11 (13%)

SBP, mmHg (mean, SD)

128.2, ± 13.7

129.1, ± 13.3

127, ± 14.1

0.268

DBP, mmHg (mean, SD)

78.9, ± 8.5

79.2, ± 8.5

78.4, ± 8.5

0.517

Fasting blood glucose, mmol/L (mean, SD)

5.9, ± 1.4

5.8, ± 1.4

6.0, ± 1.4

0.384

Total cholesterol, mg/dL (mean, SD)

206.6, ± 42.9

204.5, ± 42.4

209.5, ± 43.8

0.421

HDL cholesterol, mg/dL (mean, SD)

58.6, ± 15.0

60.0, ± 15.5

56.8, ± 14.3

0.141

LDL cholesterol, mg/dL (mean, SD)

128.3, ± 37.1

127.6, ± 36.0

129.1, ± 38.8

0.777

Triglyceride (TC), mg/dL (mean, SD)

126.4, ± 61.6

121.0, ± 57.6

133.7, ± 66.2

0.153

TC/HDL ratio (mean, SD)

3.7, ± 1.1

3.6, ± 0.9

3.9, ± 1.2

0.039

Framingham Risk Score, median (Q1, Q3)

18.2 (9.3, 28.9)

17.9 (9.6, 26.2)

18.3 (8.8, 30.5)

0.636

HeartScore, median (Q1, Q3)

2.0 (1.0, 3.0)

2.0 (1.0, 3.0)

2.0 (1.0, 4.0)

0.232

Medication usage (n, %)

    

 Not available

19 (9%)

6 (5%)

13 (16%)

0.039

 Yes

46 (23%)

30 (26%)

16 (19%)

 No

135 (68%)

80 (69%)

55 (65%)