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Table 4 Multivariable regression analysis of SIRT1 DNA methylation level (buccal smear samples)

From: DNA hypermethylation of sirtuin 1 (SIRT1) caused by betel quid chewing—a possible predictive biomarker for malignant transformation

Variables

B

Standard error

Beta

t

p value

A. Total smear samples (N = 70)

 Age

0.219

0.134

0.183

1.630

0.324

 Sex (male 1, female 2)

3.107

4.314

0.080

0.720

1.000

 Betel quid chewers vs non-chewers

11.633

3.645

0.358

3.192

0.007

B. Betel quid chewer group (N = 25)

 Age

0.189

0.396

0.095

0.478

1.000

 Sex

9.529

9.782

0.164

0.974

1.000

 Chewing years

1.280

0.455

0.558

2.814

0.031

  1. Values in italics represent statistical significance (p < 0.05); p value is calculated using Bonferroni adjustment
  2. B unstandardized coefficients, Beta standardized coefficients