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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Replication and expansion of epigenome-wide association literature in a black South African population

Fig. 6

Change in logarithmic CRP (mg/L) per % methylation change. From left to right: (i) reference EU vs. AA data, (ii) AA vs. PURE-SA-NW data and (iii) EU vs. PURE-SA-NW data. Model used for PURE-SA-NW EWAS: methylation ~ CRP + age + smoking + BMI + cells + surrogate variables. Reference data: Ligthart et al. (2016). Green data points represent CpGs where the 95% CIs for effect size estimates in each sample group overlap. Yellow data points represent CpGs where the 95% CIs for effect size estimates in each sample group do not overlap. Red data points represent the comparison of effect sizes within the reference cohorts. Black dashed line: line of equality. Blue dashed line: regression line

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Clinical Epigenetics

ISSN: 1868-7083

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