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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Replication and expansion of epigenome-wide association literature in a black South African population

Fig. 3

Change in BMI (kg/m2) per % methylation change. From left to right: (i) reference EU vs IA data, (ii) IA vs. PURE-SA-NW data and (iii) EU vs. PURE-SA-NW data. Model used for PURE-SA-NW EWAS: BMI ~ methylation + age + smoking status + alcohol consumption + physical activity + cell counts + surrogate variables. Reference data: Wahl et al. (2017). Green data points represent CpGs where the 95% CIs for effect size estimates in each sample group overlap. Yellow data points represent CpGs where the 95% CIs for effect size estimates in each sample group do not overlap. Red data points represent the comparison of effect sizes within the reference cohorts. Black dashed line: line of equality. Blue dashed line: regression line

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Clinical Epigenetics

ISSN: 1868-7083

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