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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Replication and expansion of epigenome-wide association literature in a black South African population

Fig. 1

% Methylation change per gram of alcohol intake. From left to right: (i) reference AA vs. EA data (247 CpGs), (ii) PURE-SA-NW vs. AA data (228 CpGs) and (iii) PURE-SA-NW vs. EA data (228 CpGs). Model used: methylation ~ alcohol consumption + age + BMI + cell counts + surrogate variables. Reference data: Liu et al. (2018). Green data points represent CpGs where the 95% CIs for effect size estimates in each sample group overlap. Yellow data points represent CpGs where the 95% CIs for effect size estimates in each sample group do not overlap. Red data points represent the comparison of effect sizes within the reference cohorts. Black dashed line: line of equality. Blue dashed line: regression line

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