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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Obesity-induced nucleosome release predicts poor cardio-metabolic health

Fig. 2

Associations between circulating nucleosome levels and parameters of metabolic health. Circulating nucleosomes are assayed by ELISA in Kardiovize participants (n = 120) and expressed as absorbance. a Correlation matrix between circulating nucleosome levels and cardiometabolic parameters. The data are reported as the Spearman’s correlation coefficient and those with a p value < 0.05 are indicated in bold. b Comparison of circulating nucleosome levels across metabolic health categories and its components. The data represent the median and interquartile range and are compared using the Mann-Whitney U test; ***p < 0.001; *p < 0.05. c ROC curve showing the ability of serum circulating nucleosomes to discriminate patients with poor metabolic health. SBP systolic blood pressure, DBP diastolic blood pressure, TG triglycerides

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