Skip to main content

Table 4 Association between rs4808844A>G and weight parameters in an independent psychiatric sample without available methylation data

From: Psychotropic drug-induced genetic-epigenetic modulation of CRTC1 gene is associated with early weight gain in a prospective study of psychiatric patients

 

Early weight gain1

Weight (kg)2

n

Estimate (SE)

p value

n

Estimate (SE)

p value

rs4808844 A>G [G]

131

− 0.66 (0.40)

0.10

568

− 1.55 (1.2)

0.07

  1. 1A logistic model adjusting for age, sex, psychotropic drug category, smoking status, and treatment duration was fitted in patients with available genetic data for rs4808844 and with available weight at baseline and after the first month of treatment
  2. 2A GAMM adjusting for age, sex, psychotropic drug category, smoking status, and treatment duration was fitted in patients with available weight and genetic data for rs4808844