Fig. 3From: Comprehensive longitudinal study of epigenetic mutations in agingProportions of high methylation outliers (HMOs) and low methylation outliers (LMOs) in different CpG island regions. HMOs are enriched in CpG islands (p < 1e-16) while LMOs are more distributed outside of CpG islands (p < 1e-16), especially in open sea regions. However, both frequent HMOs and LMOs are enriched in CpG islands (p < 1e-16 and p = 8.6e-8)Back to article page