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Fig. 6 | Clinical Epigenetics

Fig. 6

From: DNMT1 recruited by EZH2-mediated silencing of miR-484 contributes to the malignancy of cervical cancer cells through MMP14 and HNF1A

Fig. 6

MMP14 and HNF1A promotes CC cell adhesion, migration, and invasion. a and b The influence of MMP14 (a) and HNF1A (b) on β-integrin, E-cadherin, vimentin protein expression in HeLa cells was determined by Western blot. c and d Cell–cell adhesion assay (c) and cell–matrix adhesion assay (d) of HeLa cells after transfection with pFlag-MMP14/HNF1A or shR-MMP14/HNF1A. e and f Transwell migration (e) and invasion assays (f) of HeLa cells after transfection with pFlag-MMP14/HNF1A or shR-MMP14/HNF1A. All of the experiments were repeated three times. *p < 0.05, **p < 0.01, ***p < 0.001

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Clinical Epigenetics

ISSN: 1868-7083

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