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Fig. 5 | Clinical Epigenetics

Fig. 5

From: ZMYND10, an epigenetically regulated tumor suppressor, exerts tumor-suppressive functions via miR145-5p/NEDD9 axis in breast cancer

Fig. 5

Overexpressed ZMYND10 suppressed breast cancer cell migration and invasion ability. a The cellular migration abilities were examined by wound healing assays in MDA-MB231 and SK-BR-3 stably transfected with ZMYND10 or empty vector plasmid. Left, photographs were captured at 0 h and 48 h. Right, the ratio of wound healing was calculated. *p < 0.05,**p < 0.01, ***p < 0.001. b Representative image(left) and quantification (right) of transwell migration assay conducted with stably transfected MDA-MB231 and SK-BR-3 cells, × 200. c Representative image (left) and quantification (right) of transwell invasion assay conducted with stably transfected MDA-MB231 and SK-BR-3 cells, × 200. ***p < 0.001

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