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Table 2 The four most statistically significant canonical pathways from IPA

From: Changes in DNA methylation from pre- to post-adolescence are associated with pubertal exposures

PathwaysRatiop valueCpG sitesGenes
Amyotrophic Lateral Sclerosis Signaling0.0810.00026cg01483824GRIN2D
cg05404236IRS2
cg05942459GRIK2
cg14029489PRPH
cg19318393CAPN2
cg20681578AKT3
cg22562942NEFM
cg23786580HECW1
cg26746936GRIK5
G-Protein Coupled Receptor Signaling0.0500.0010cg00456868CHRM5
cg01207684ADCY9
cg01939453PDE10A
cg02914422PDE1C
cg05404236IRS2
cg10273340GNAO1
cg11701471OPRK1
cg11934695ADRA1D
cg19908812NPY1R
cg20681578AKT3
cg21213853GRM2
cg23817981CCR4
cg24540003RELA
Relaxin Signaling0.0570.0032cg01207684ADCY9
cg01939453PDE10A
cg02914422PDE1C
cg05404236IRS2
cg10273340GNAO1
cg20681578AKT3
cg24540003RELA
cg25599619GNB1
IL-17A Signaling in Airway Cells0.0770.0036cg05404236IRS2
cg15053248MAP3K7
cg15931839TRAF3IP2
cg20681578AKT3
cg24540003RELA
  1. [1] Ratio is the number of genes in our list to the number of genes in a pathway [2]. CpGs and genes identified in at least two pathways are in bold font