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Table 1 Clinical and pathological features of LC, PCa and CRC patient and ACs included in this study

From: Early detection of the major male cancer types in blood-based liquid biopsies using a DNA methylation panel

Clinicopathological features

AC

Cancer patients

Number

136

323

Age median (range)

57 (48–66)

68 (27–93)

Lung cancer

 Number

 

102

 Age median (range)

 

66 (45–89)

 Histological type

n.a.

 

  Non-small cell lung carcinoma (NSCLC)

 

   Adenocarcinoma

42

   Squamous cell carcinoma

43

   Large cell carcinoma

1

  Small cell lung carcinoma (SCLC)

16

 Primary tumour (T)a

n.a.

 

  T1

12

  T2/T3/T4

82

 Regional lymph node (N)b

n.a.

 

  N0

25

  N+

72

 Distant metastasis (M)

n.a.

 

  M0

47

  M+

55

 Clinical stage

n.a.

 

  I/II

17

  III/IV

85

Prostate cancer

 Number

 

121

 Age median (range)

 

71 (52–88)

 Histological type

n.a.

 

  Adenocarcinoma

121

 Primary tumour (T)c

n.a.

 

  T1/T2

104

  T3

16

 Regional lymph node (N)

n.a.

 

  N0

119

  N+

2

 Distant metastasis (M)

n.a.

 

  M0

116

  M+

5

 Grade group

n.a.

 

  1

59

  2

38

  3/4/5

24

 Serum PSA levels (ng/mL)

n.a.

 

  < 10

71

  10–20

27

  > 20

23

 Clinical stage

n.a.

 

  I

31

  II

55

  III/IV

35

Colorectal cancer

 Number

 

100

 Age median (range)

 

66 (27–93)

 Histological Type

n.a.

 

  Adenocarcinoma (all subtypes)

99

  Squamous cell carcinoma

1

 Tumour location

n.a.

 

  Proximal colon

23

  Distal colon

36

  Rectum

41

 Primary tumour (T)d

n.a.

 

  T1/T2

26

  T3/T4

72

 Regional lymph node (N)e

n.a.

 

  N0

40

  N+

57

 Distant metastasis (M)

n.a.

 

  M0

82

  M+

18

 Clinical stage

n.a.

 

  I/II

39

  III/IV

61

  1. aNo information available in 8 cases
  2. bNo information available in 5 cases
  3. cNo information available in 1 case
  4. dNo information available in 2 cases
  5. eNo information available in 3 cases
  6. n.a. not applicable