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Table 4 ANKRD26 gene expression in relation to metabolic and inflammatory parameters. Relationship between metabolic or inflammatory parameters and ANKRD26 gene expression was assessed in lean and obese individuals by covariate-adjusted Spearman’s rank-order correlation adjusted for age. Number of individuals (n), correlation coefficient r, and age-adjusted p value are shown in the table. TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; CRP, C-reactive protein; IL, interleukin; IFNγ, interferon γ; TNFα, tumor necrosis factor α; IP-10, interferon gamma-induced protein 10; MCP1, monocyte chemotactic protein 1; MIP1, macrophage inflammatory protein 1; RANTES, regulated on activation, normal T cell expressed, and secreted

From: Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity

Parameters

Gene expression

n

r

p value

Glucose

34

− 0.233

n.s.

TG

34

− 0.630

< 0.001

TC

34

− 0.113

n.s.

HDL-C

34

0.647

< 0.001

LDL-C

34

− 0.315

n.s.

CRP

34

− 0.494

0.001

IL-1β

30

− 0.498

0.010

IL-6

30

− 0.401

0.027

IL-7

30

− 0.185

n.s.

IL-9

30

− 0.123

n.s.

IL-12

30

− 0.506

0.002

IL-17

30

− 0.085

n.s.

IFN-γ

30

− 0.112

n.s.

TNF-α

30

− 0.037

n.s.

IL-8

30

− 0.650

< 0.001

Eotaxin

30

− 0.116

n.s.

IP-10

30

− 0.520

0.002

MCP-1

30

− 0.206

n.s.

MIP-1α

30

− 0.513

0.006

MIP-1β

30

− 0.601

< 0.001

RANTES

30

− 0.476

0.002