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Table 1 Anthropometric and biochemical features of lean (n = 14; 7 males and 7 females) and obese (n = 20; 10 males and 10 females) individuals. For symmetrically distributed variables, data are shown as mean ± SD and statistical difference between the two groups was tested by two-tailed unpaired Student’s t test. For skewed distributions, data are shown as median (first quartile—Q1; third quartile—Q3) and statistical differences between the two groups were tested using Mann-Whitney U test. BMI, body mass index; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride; CRP, C-reactive protein

From: Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity

 

Lean

Obese

p value

n (males/females)

14 (7/7)

20 (10/10)

 

Age (years)

30.2 ± 2.6

37.0 ± 5.6

< 0.001

BMI (kg m−2)

22.3 ± 2.7

46.7 ± 6.9

< 0.001

Glucose (mg dL−1)

87.9 ± 7.1

95.4 ± 37.3

n.s.

TC (mg dL−1)

176.4 ± 33.4

179.1 ± 37.3

n.s.

HDL-C (mg dL−1)

63.9 ± 20.4

46.5 ± 10.2

0.002

LDL-C (mg dL−1)

94.9 ± 31.6

117.8 ± 29.2

0.037

TG (mg dL−1)

58.6 (43.4; 83.6)

119.5 (90.2; 162.0)

< 0.001

TG/HDL-C ratio

0.9 (0.6; 1.9)

2.6 (1.8; 4.2)

< 0.001

CRP (mg L−1)

0.2 (0.1; 0.4)

7.7 (1.7; 14.4)

< 0.001