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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity

Fig. 3

ANKRD26 gene expression, promoter methylation, and BMI. a Relationship between ANKRD26 gene expression and the combined DNA methylation at the CpGs − 689, − 659, and − 651 was assessed in lean (n = 14) and obese individuals (n = 20) by covariate-adjusted Spearman’s rank-order correlation adjusted for age. r = − 0.539, age-adjusted p < 0.001. b Relationship between BMI and the combined DNA methylation at the CpGs − 689, − 659, and − 651 was assessed in lean (n = 14) and obese individuals (n = 20) by covariate-adjusted Spearman’s rank-order correlation adjusted for age. r = 0.736, age-adjusted p < 0.001

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