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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity

Fig. 1

ANKRD26 mRNA levels in PBL of lean and obese subjects. a ANKRD26 mRNA levels were determined in lean (n = 14) and obese (n = 20) subjects. Values are expressed in absolute units (AU) and their distribution within each group is represented by box plots. Box plots show median (line within the box), quartiles (upper and lower box boundaries), and extreme values (whiskers). Statistical differences between the two groups were tested using nonparametric quantile regression, with inference based on median, to adjust for age. p = 0.027 vs. lean. b Relationship between BMI and ANKRD26 gene expression was assessed by covariate-adjusted Spearman’s rank-order correlation adjusted for age. n = 34; r = − 0.494; p = 0.002

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