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Table 2 Initial histopathological diagnoses

From: The central nervous system tumor methylation classifier changes neuro-oncology practice for challenging brain tumor diagnoses and directly impacts patient care

Tumor type (n = 55)

N

%

Diffuse glioma

Diffuse astrocytoma, IDH mutant

4

7

Diffuse astrocytoma, IDH1 (R132H) negative

2

4

Anaplastic astrocytoma, IDH mutant

2

4

Anaplastic astrocytoma, IDH1 (R132H) negative

3

5

Oligodendroglioma, IDH1 (R132H) negative, 1p/19q co-deleted

2

4

Anaplastic oligodendroglioma, IDH1 (R132H) negative, 1p/19q co-deleted

3

5

Glioblastoma, IDH1 (R132H) negative

11

20

Glioma NOS

3

5

Low grade glioma

1

2

Diffuse low grade glioma

1

2

Other astrocytic

Pilocytic astrocytoma

1

2

PXA

1

2

Anaplastic PXA

2

4

Ependymal

Subependymoma

2

4

Ependymoma

1

2

Anaplastic ependymoma

3

5

Choroid plexus

Atypical choroid plexus papilloma

1

2

Neuronal

Dysembryoplastic neuroepithelial tumor

1

2

Ganglioglioma variant

2

4

Embryonal

Medulloblastoma

3

5

Nerves

Schwannoma

1

2

Meningioma

Atypical meningioma

1

2

Mesenchymal

SFT/hemangiopericytoma

1

2

Metastatic

Melanocytic lesion NOS

1

2

Metastatic high-grade NE neoplasm

1

2

Non-neoplastic

Meningioangiomatosis

1

2

  1. NOS not otherwise specified, PXA pleomorphic xanthoastrocytoma, SFT solitary fibrous tumor, NE neuroendocrine