Table 4 Annotations for the nine overlapping CpGs for the cisplatin-based chemotherapy (CBCT) model and metabolic syndrome (MetS) model for the 2000 CpGs with the lowest unadjusted p values < 0.05

cg25165017

< 0.001

0.001

cg27087650

BCL3

< 0.001

0.012

Contributes to the regulation of cell proliferation

cg10785263

< 0.001

0.020

cg17986793

MX1

< 0.001

0.022

Gene product, Interferon-induced GTP-binding protein Mx1 is a protein that in humans is encoded by the MX1 gene

cg10587886

LMCD1-AS1

< 0.001

0.044

LMCD1 antisense RNA 1

cg18871648

ELMSAN1

< 0.001

0.050

ELM2 and Myb/SANT domain containing 1

cg07688244

< 0.001

0.098

cg14792781

GRHL1

< 0.001

0.127

This gene encodes a member of the grainyhead family of transcription factors. The encoded protein can exist as a homodimer or can form heterodimers with sister-of-mammalian grainyhead or brother-of-mammalian grainyhead. This protein functions as a transcription factor during development

cg25273039

NXPH1

< 0.001

0.165

The product protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons

Waist-to-hip ratio adjusted for body mass index, Obesity-related traits

cg19509829

ATP2A2

< 0.001

0.215

Product Belongs to a family of ATPase enzymes that helps control the level of positively charged calcium atoms (calcium ions) inside cells

Glucose homeostasis traits