Fig. 3
From: Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome
Functional gene networks of cisplatin-based chemotherapy (a) and metabolic syndrome (b) related genes reconstructed using the GENIUS tool. Nodes represent genes and edges (arrows) show the directions of the interactions found. Size of nodes is proportional to a gene network degree (number of neighbors of a given gene in the network). A node color intensity represents significance from the differential methylation analysis (high intensity colors represent highly significant genes, adjusted p value for panel (a) and unadjusted p value for panel (b) shown). Nodes marked with black circles represent genes associated with any of the metabolic syndrome trait