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Table 2 MMGBSA calculated binding energies (ΔG) for MC4040 and MC4041

From: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype

LigandIC50 (μM)GBSA ΔG (kcal/mol)
MC40404.06-23.0432
MC40411.06-30.4428